antileukemic activity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T24269	KPT-251	KPT251	Others
	KPT-251 is a selective nuclear export inhibitor.		Others
TN4673	(+)-Nortrachelogenin	Wikstromol	Apoptosis , HIV Protease , PI3K , Antifection
	(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.		Apoptosis , HIV Protease , PI3K , Antifection
TN1932	Microhelenin C		Others
	Microhelenin C has significant antileukemic activity.		Others
T5S1058	Triptonide	PG 492,NSC 165677	Apoptosis , Wnt/beta-catenin , Autophagy
	1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, an...		Apoptosis , Wnt/beta-catenin , Autophagy
T25503	Hisphen	Synonyms Hisfen,MD 2
	Hisphen shows antileukemic activity.
TN2320	Yadanzioside G		Others
	Yadanzioside G has antileukemic activity.		Others
TN5266	Yadanzioside F		Others
	Yadanzioside F has antileukemic activity.		Others
TN5092	Tagitinin F		Antifection
	Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes.		Antifection
TN4027	Eucannabinolide		Others
	Eucannabinolide exhibits in vivo antileukemic activity.		Others
TN3796	Dehydrobruceantinol		Others
	Dehydrobruceantinol shows bitter taste and has antileukemic activity.		Others
T15472	Hepsulfam	NCI 329680,ZINC01574758	Others
	Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).		Others
T24492	Moflomycin	F 860191,F-860191,F860191
	Moflomycin is an anthracycline derivative. It exhibits a higher antileukemic activity compared to other anthracyclines.
TN5265	Yadanzioside C		Others
	Yadanzioside C has antileukemic activity.		Others
TN2319	Yadanzioside A		Others
	Yadanzioside A has antileukemic activity.		Others
TN3542	Bruceantinoside A		Others
	Bruceantinoside A has antileukemic activity.		Others
T25170	Botryodiplodin	Cytostipin,Antibiotic PSX 1
	Botryodiplodin, an antibiotic, has antileukemic activity from Botryodiplodia theobromae. It has the property of turning the skin of the individual in various shades of pink 2-3 hrs after application. It is a toxic metabo...
T22132	PD 166326
	PD166326, a pyridopyrimidine-type inhibitor of receptor tyrosine kinases, demonstrates antileukemic activity with IC50 values of 6 nM for Src and 8 nM for Abl. [1] [2].
T60559	S-(N-PhenethylthiocarbaMoyl)-L-cysteine
	S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) is an anticarcinogenic agent. S-(N-PhenethylthiocarbaMoyl)-L-cysteine shows antileukemic activity which inhibits DNA synthesis in HL60 cells [1]. S-(N-Phenethylthiocarb...
T82774	Caspase-3 activator 3		Caspase
	Caspase-3 activator 3 (compound 2h) effectively induces apoptosis in HL-60 and K562 cells by substantially activating caspase-3, demonstrating antileukemic activity with IC50 values of 42.89 μM and 33.61 μM, respectively...		Caspase
T73167	HDAC-IN-49
	HDAC-IN-49 is a potent, non-selective inhibitor of HDAC (HDAC), demonstrating IC50 values of 13 nM for HDAC1, 14 nM for HDAC2, 21 nM for HDAC3, 1880 nM for HDAC4, and 10 nM for HDAC6. This compound exhibits significant a...